Induces Neovascularization Through Angiogenesis.

 

Human CD34+ stem cell-derived exosomes mediate pro-angiogenic paracrine activity.

 

CD34+ exosomes induce the formation of vessel-like endothelial structures.

 

CD34+ exosomes are most effectively internalized by endothelial cells in ischemic tissue, resulting in cell cycle induction, angiogenesis, and proliferation.

 

Applications: Ischemic Stroke, Peripheral Artery Disease, Skin Flap Grafting, Diabetic Foot Disease, Myocardial Infarction, Retinal Ischemia, Ischemic-Based Diseases.